Chymotrypsinogen: Increased Resolution and Absolute Configuration.
نویسندگان
چکیده
* Research carried out at Brookhaven National Laboratory under the auspices of the U.S. Atomic Energy Commission. 1 Tissibres, A., J. D. Watson, D. Schlessinger, and B. R. Hollingworth, J. Mol. Biol., 1, 221 (1959). 2 Zubay, G., in Recent Progress in Microbiology (Montreal: University of Toronto Press, 1962), p. 65. 3 Gilbert, W., J. Mol. Biol., 6, 374 (1963). 4 Nirenberg, M. W., and J. H. Matthaei, these PROCEEDINGS, 47, 1588 (1961). 5 Brenner, S., F. Jacob, and M. Meselson, Nature, 190, 576 (1961). 6 Gros, F., H. Hiatt, W. Gilbert, C. G. Kurland, R. W. Risebrough, and J. D. Watson, Nature, 190, 581 (1961). 7 Takanami, M., and T. Okamoto, J. Mol. Biol., 7, 323 (1963). 8 Warner, J. R., A. Rich, and C. E. Hall, Science, 138, 1399 (1962). 9Littauer, V. Z., and A. Kornberg, J. Biol. Chem., 227, 1077 (1957). 10 Singer, M. F., and J. K. Guss, J. Biol. Chem., 237, 182 (1962). Nomura, M., B. D. Hall, and S. Spiegelman, J. Mol. Biol., 2, 306 (1960). 12Marcus, L., R. K. Bretthauer, R. M. Bock, and H. 0. Halvorson, these PROCEEDINGS, 50, 782 (1963). 13Jones, 0. W., E. E. Townsend, H. A. Sober, and L. A. Heppel, Biochemistry, 3, 238 (1964). 14 Zubay, G., Science, 140, 1092 (1963). 15Huxley, H. E., and G. Zubay, J. Mol. Biol., 2, 10 (1960). 16Barondes, S. H., and M. W. Nirenberg, Science, 138, 813 (1962). 17 Okamoto, T., and M. Takanami, Biochim. Biophys. Acta, 76, 266 (1963). 18Fresco, J. R., and E. Klemperer, Ann. N.Y. Acad. Sci., 81, 739 (1959).
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 51 شماره
صفحات -
تاریخ انتشار 1964